Christopher Chance makes his living by turning himself into a human target. A master of disguise, he cunningly takes on the appearance and persona of men and women with contracts out against them. But when a routine assignment to impersonate an African-American minister with a bounty on his head goes south, Chance finds himself caught between a lethal assassin and a vicious gang war. After the assignment changes his life completely, Chance’s next adventure takes him into the world of Hollywood as he impersonates an aging actor to find a missing boy and flirts with the idea of leaving his dangerous life behind him.

This volume collects the original 4-issue Vertigo Human Target miniseries with art by Edvin Biukovic along with the follow-up, standalone, 96-page Human Target: Final Cut with art by Javier Pulido (Robin: Year One).